查看完整版本: Review of Quantum Dot Technologies for Cancer Detection and Treatment

Review of Quantum Dot Technologies for Cancer Detection and Treatment

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Sandeep Kumar Vashist, Rupinder Tewari, Ram Prakash Bajpai, Lalit Mohan Bharadwaj and Roberto Raiteri[/i]
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[b]Topics Covered  [/b]._oOD/]~
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[color=DarkGreen][b]Abstract[/b][/color]S kJ;`:Jg
[color=DarkGreen][b]Introduction[/b][/color]
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u)Z [color=DarkGreen][b]Quantum Dots in Early Diagnosis of Cancer[/b][/color]5Q2B7`+b9BmC7Gee"i
[color=DarkGreen][b]Advantages of Inorganic Quantum Dots over Organic Fluorophores[/b][/color]Z!Lf X)gz!H
[color=DarkGreen][b]Quantum Dot Technology[/b][/color]
`E0@.e1k |-C.SX [color=DarkGreen][b]Synthesis of Quantum Dots[/b][/color]|k)k@9_['p
[color=DarkGreen][b]Properties and Applications of Quantum Dots[/b][/color]
HNX*j m/D:IH [color=DarkGreen][b]Overcoming the Toxic Nature of Quantum Dots[/b][/color]v?)j}C'P
[color=DarkGreen][b]Blinking Behavior of Quantum Dots[/b][/color]Q v.S)p}\.|
[color=DarkGreen][b]Effect of Surface Functionalization on the Optical Properties of Quantum Dots[/b][/color])bK$LXii V,A}
[color=DarkGreen][b]Measurement System for Observing and Tracking Quantum dots[/b][/color]
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z [color=DarkGreen][b]Active and Passive Quantum Dot Targeting Mechanisms[/b][/color]AP\5a+i0is#p8t}
[color=DarkGreen][b]Deep Tissue Imaging Requirements[/b][/color]
ql2@sT\ n0j [color=DarkGreen][b]Removal of Quantum Dots from Living Cells[/b][/color]
G9r:r1ay#L(d1j7V [color=DarkGreen][b]Potential Applications of Quantum Dots in Disease Diagnosis and Treatment[/b][/color]
rwi7Yz)_!i [color=DarkGreen][b]Conjugation of Biomolecules to Quantum Dots[/b][/color] ^#ea.M:|6L
[color=DarkGreen][b]Strategies to Modify Biomolecules[/b][/color]
qHb0P9Fw7hJ4[MQ [color=DarkGreen][b]Effects of Quantum Dots on Biological Functions of Biomolecules[/b][/color]
:C+q9N3QC [color=DarkGreen][b]Advances in Quantum Dot Technology for the Diagnosis of Cancer[/b][/color]

Nr]c? ^1c [color=DarkGreen][b]Quantum Dot-Peptide Conjugates Shown to Target Tumour Cells[/b][/color]6I`7FZm/P}Z(a)_
[color=DarkGreen][b]Quantum Dots Able to identify Live Breast Cancer Cells[/b][/color]5wu!]2`4u5G
[color=DarkGreen][b]Multifunctional Quantum Dots Simultaneously Target and Image Tumours in Living Animals[/b][/color]aF!k;h3~3X1~1k(@
[color=DarkGreen][b]Near Infrared Quantum Dots for Sentinel Lymph Node Mapping[/b][/color]#H.A E&c^A
[color=DarkGreen][b]Quantum Dots for Multiplexed Analysis[/b][/color]
T%P'jzX,Nn [color=DarkGreen][b]Self-Illuminating Quantum Dots for in vivo Imaging[/b][/color]4kt5{ h_uL
[color=DarkGreen][b]Quantum Dot Based Drug Delivery System to Target Cancer[/b][/color]}J5X-QN"M
[color=DarkGreen][b]The Current State of Play[/b][/color]~K H%kH6f
[color=DarkGreen][b]Future Applications of Quantum Dots in Cancer Diagnosis and Treatment[/b][/color]
*m.HQ6{i8Mnx%N\ [color=DarkGreen][b]References[/b][/color]
&|9Qr3G{ JFt [/quote][table=98%][tr][td=2,1]Abstract   [/td] [/tr] [tr][td]  Semiconductorquantum dots (QDs) are nanoparticles that have attracted widespreadinterest in biology and medicine due to their unique optical andelectronic properties. These properties, especially their reducedtendency to photobleach and the dependence of their fluorescencewavelength on their size, make them suitable for fluorescent probingapplications to detect cancer biomarkers [i]in vitro[/i] and [i]in vivo[/i]in cells/tissues/whole body. There is considerable interest amongresearchers due to the recent developments in QD technology. QDs havebeen encapsulated in amphiphilic polymers and bound to tumor-targetingligands and drug delivery vesicles for targeting, imaging and treatingtumor cells. Present efforts are focussed on exploring the massivemultiplexing capabilities of the QDs for the simultaneous detection ofmultiple cancer biomarkers in blood assays and cancer tissue biopsies.These advances in the QD technology have unravelled a great deal ofinformation about the molecular events in tumor cells and earlydiagnosis of cancer.ff6A.WlS;pP7Ir
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[[i] 本帖最后由 nanoquebec 于 2006-11-27 14:39 编辑 [/i]]