nano 2007-08-29 04:15
Nanoencapsulation I and II
[b][size=5]Nanoencapsulation I. Methods for preparation of drug-loaded polymeric nanoparticles[/size][/b]
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[b][i]Nanomedicine: Nanotechnology, Biology and Medicine[/i][/b], Volume 2, Issue 1, March 2006, Pages 8-21
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Catarina Pinto Reis PhDa, Ronald J. Neufeld PhDb, Corresponding Author Contact Information, E-mail The Corresponding Author, António J. Ribeiro, PhDc and Francisco Veiga PhDa
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aLaboratório Tecnologia Farmacêutica, Faculdade de Farmácia, Universidade de Coimbra, Coimbra, Portugal
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bChemical Engineering Department, Queen’s University, Kingston, Ontario, Canada
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cDepartamento Tecnologia Farmacêutica, I.S.C.S.N., Gandra, Paredes, Portugal}i]pq-TI!W
Received 21 August 2005; accepted 20 December 2005. Available online 18 March 2006.SWL~ J
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AbstractPTP|8jS@C
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Polymeric nanoparticles have been extensively studied as particulate carriers in the pharmaceutical and medical fields, because they show promise as drug delivery systems as a result of their controlled- and sustained-release properties, subcellular size, and biocompatibility with tissue and cells. Several methods to prepare nanoparticles have been developed during the last two decades, classified according to whether the particle formation involves a polymerization reaction or arises from a macromolecule or preformed polymer. In this review the most important preparation methods are described, especially those that make use of natural polymers. Advantages and disadvantages will be presented so as to facilitate selection of an appropriate nanoencapsulation method according to a particular application.
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[url=http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B7MDB-4JH72D0-3&_user=1022551&_coverDate=03%2F31%2F2006&_rdoc=3&_fmt=summary&_orig=browse&_srch=doc-info(%23toc%2323226%232006%23999979998%23619248%23FLA%23display%23Volume)&_cdi=23226&_sort=d&_docanchor=&view=c&_ct=8&_acct=C000050484&_version=1&_urlVersion=0&_userid=1022551&md5=1a145f199c1f65fc214f809f30c20027]:fulltext :link[/url]
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[b][size=5][b]Nanoencapsulation II. Biomedical applications and current status of peptide and protein nanoparticulate delivery systems[/b][/size][/b]2Ie6ePE}
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[b][i]Nanomedicine: Nanotechnology, Biology and Medicine[/i][/b], Volume 2, Issue 2, June 2006, Pages 53-65F.U+[0wP,k
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Catarina Pinto Reis MSa, Ronald J. Neufeld PhDb, Corresponding Author Contact Information, E-mail The Corresponding Author, António J. Ribeiro PhDc and Francisco Veiga PhDa
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aLaboratorio Tecnologia Farmacêutica, Faculdade de Farmácia, Universidade de Coimbra, Coimbra, Portugal(Bn,y+iAm#m
bDepartment of Chemical Engineering, Queen's University, Kingston, Ontario, Canada%{HA ZC
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cDepart. Tecnologia Farmacêutica, I. S. C. S. N.-C. E. S. P. U., Gandra, Paredes, Portugal0|5zl2ck jQ
Received 10 April 2006; accepted 12 April 2006. Available online 15 June 2006.)tug&E-f:j