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nano 2007-08-29 04:15

Nanoencapsulation I and II

[b][size=5]Nanoencapsulation I. Methods for preparation of drug-loaded polymeric nanoparticles[/size][/b]
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[b][i]Nanomedicine: Nanotechnology, Biology and Medicine[/i][/b], Volume 2, Issue 1, March 2006, Pages 8-21
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u?Q R0r1icb6r Catarina Pinto Reis PhDa, Ronald J. Neufeld PhDb, Corresponding Author Contact Information, E-mail The Corresponding Author, António J. Ribeiro, PhDc and Francisco Veiga PhDa
O"q z[7s/IG*|d aLaboratório Tecnologia Farmacêutica, Faculdade de Farmácia, Universidade de Coimbra, Coimbra, Portugal
0r&\8Na:O/dI bChemical Engineering Department, Queen’s University, Kingston, Ontario, Canada
.v5r&jC6G|*W k cDepartamento Tecnologia Farmacêutica, I.S.C.S.N., Gandra, Paredes, Portugal}i]pq-T I!W
Received 21 August 2005;  accepted 20 December 2005.  Available online 18 March 2006.SWL~ J

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Polymeric nanoparticles have been extensively studied as particulate carriers in the pharmaceutical and medical fields, because they show promise as drug delivery systems as a result of their controlled- and sustained-release properties, subcellular size, and biocompatibility with tissue and cells. Several methods to prepare nanoparticles have been developed during the last two decades, classified according to whether the particle formation involves a polymerization reaction or arises from a macromolecule or preformed polymer. In this review the most important preparation methods are described, especially those that make use of natural polymers. Advantages and disadvantages will be presented so as to facilitate selection of an appropriate nanoencapsulation method according to a particular application.
t"fYp-kdh1~ [url=http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B7MDB-4JH72D0-3&_user=1022551&_coverDate=03%2F31%2F2006&_rdoc=3&_fmt=summary&_orig=browse&_srch=doc-info(%23toc%2323226%232006%23999979998%23619248%23FLA%23display%23Volume)&_cdi=23226&_sort=d&_docanchor=&view=c&_ct=8&_acct=C000050484&_version=1&_urlVersion=0&_userid=1022551&md5=1a145f199c1f65fc214f809f30c20027]:fulltext :link[/url]
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6SU~UA-R [b][size=5][b]Nanoencapsulation II. Biomedical applications and current status of peptide and protein nanoparticulate delivery systems[/b][/size][/b]2Ie6ePE}
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[b][i]Nanomedicine: Nanotechnology, Biology and Medicine[/i][/b], Volume 2, Issue 2, June 2006, Pages 53-65F.U+[0w P,k

S+Urs lt^ [ Catarina Pinto Reis MSa, Ronald J. Neufeld PhDb, Corresponding Author Contact Information, E-mail The Corresponding Author, António J. Ribeiro PhDc and Francisco Veiga PhDa
'V'L(Qd$D aLaboratorio Tecnologia Farmacêutica, Faculdade de Farmácia, Universidade de Coimbra, Coimbra, Portugal(Bn,y+iAm#m
bDepartment of Chemical Engineering, Queen's University, Kingston, Ontario, Canada%{HA ZC w
cDepart. Tecnologia Farmacêutica, I. S. C. S. N.-C. E. S. P. U., Gandra, Paredes, Portugal0|5zl2ck jQ
Received 10 April 2006;  accepted 12 April 2006.  Available online 15 June 2006.)tug&E-f:jX
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Abstract v5y"ij9Kc

_'T{'Q6?&l The concept of polymeric nanoparticles for the design of new drug delivery systems emerged a few years ago, and recent rapid advances in nanotechnology have offered a wealth of new opportunities for diagnosis and therapy of various diseases. Recent progress has made possible the engineering of nanoparticles to allow the site-specific delivery of drugs and to improve the pharmacokinetic profile of numerous compounds with biomedical applications such as peptide and protein drugs. Biologically active peptides and their analogues are becoming an increasingly important class of drugs. Their use for human and animal treatment is problematic, however, because some of these drugs are generally ineffective when taken orally and thus have been administered chiefly by the parenteral route. This review covers some of the historical and recent advances of nanotechnology and concludes that polymeric nanoparticles show great promise as a tool for the development of peptide drug delivery systems. ?RG`O9r
[url=http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B7MDB-4K674VB-2&_user=1022551&_coverDate=06%2F30%2F2006&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050484&_version=1&_urlVersion=0&_userid=1022551&md5=58381dbd3dc27922d246904952b5a0de]
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styrene 2007-08-29 07:51

:victory: :victory:

leotron 2007-08-29 08:44

thanks a lot. good book.

tooold 2007-08-29 08:44

回复 #1 nano 的帖子

hao!!!!!!!!!!!!!!!!

大森林 2007-08-29 08:46

不错顶一个!!!!!!!!!!!!!!!

zhangdelin0000 2007-08-29 08:52

好东西,强烈支持楼主!!!

xieyeld 2007-08-29 09:31

:victory: :lol :Q

biyu 2007-08-29 11:08

:handshake :handshake

punkx 2007-08-29 15:15

Nanoencapsulation nanoparticles

Hdeu 2007-09-02 23:14

well done,强烈支持楼主

sharat_c 2007-09-02 23:32

Reply #1 nano's post

thanks a lot.

bankkom 2007-09-02 23:33

:victory: :victory: :handshake

gengxin60 2007-09-03 08:08

:lol ,good,:handshake

tombraider 2007-09-03 11:14

Nanoencapsulation I. Methods for preparation of drug-loaded polymeric nanoparticles

a_stranger 2007-09-05 15:02

Thanks! :victory:

fatebird 2007-09-19 15:09

正在找这方面的资料那哈哈,谢谢了

电泳 2007-09-20 10:54

谢谢哦,不错的,谢谢hi:lol :D

H2O 2007-09-25 00:43

thanks.:victory: :victory:

lsh197635 2007-09-25 07:43

thanks               a                           lot

nanohp 2007-09-25 08:02

不错:D :D :D
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