phcaobq 2007-11-13 03:32
Nanomedicine--Global Technology Developments and Growth Opportunities
Targeted Therapy and Fewer Side Effects Bolster the Case for Nanomedicine
The potential of emerging nanomedicine technologies to provide site-specific therapeutic action with a better side effects profile is a strong point in favor of this pioneering form of medicine. With the advent of nanomedicine and techniques for the early diagnosis of diseases, prophylactic or preventive intervention could receive a big fillip. The medical implications of such prophylactic interventions are huge: treatment could be started even before initial symptoms manifest; diseases could be warded off or even completely avoided in some instances. With such immense possibilities, nanomedicine could well hold the key to a vastly improved quality of life and physical well-being for individuals.
This Technical Insights research analyzes and presents prospective therapeutic and diagnostic applications of nanotechnology in medicine. It discusses exciting global developments in nanomedicine, focusing on ground-breaking research and technologies already gaining popularity in various parts of the world. The study also covers technology, business, and regulatory challenges, market drivers and restraints, and major research trends.
Adoption of Nanotechnology by Big Therapeutic and Diagnostic Companies Gives an Impetus to Nanomedicine
Pharmaceuticals, biopharmaceuticals, and drug delivery companies are increasingly adopting nanotechnology-based applications. A good case in point is the use of NanoCrystal technology by leading pharmaceutical companies for drug development and new chemical entities (NCEs). NanoCrystal technology has multiple applications in drug formulation and can be incorporated in a variety of oral dosage presentations such as tablets, capsules, liquid dispersions, and powders. Additionally, this technology offers an effective screening tool for NCEs in the discovery phase of new drug development.
This encouraging trend is seen in the growing use of quantum dot particles as well. "Some of the world?fs largest pharmaceutical companies, biotech firms, and top academic research centers are applying quantum dots in high-content drug screening and have completed initial drug screens using these particles as the biological read-out. Quantum dots are also being applied in the detection of breast cancer cells," says the analyst of this research service.
Need to Integrate Technology Expertise Across a Multitude of Disciplines Becomes Imperative
"Drug and medical device development calls for the coming together of a variety of scientific disciplines: chemistry, biology, information sciences, statistics, pharmacology, to name a few. Nanomedicine companies face the daunting challenge of developing expertise in a wide range of technologies," states the analyst.
Industry and academia are both experiencing significant innovation, signaling a bright future for nanomedicine. Nanomedical companies must consider forming synergistic partnerships with drug and medical device companies to aid the go-to-market process, at least initially. As the technology and the market continue to develop, companies can aim to become full-fledged participants operating on their own.
Table Of Contents
1. Executive Summary
1. Introduction
1. Introduction to Nanotechnology
2. Nanomedicine?An Overview
2. Scope and Methodology
1. Scope and Segmentation of the Research Service
2. Methodology
2. Nanomedicine: Growth Opportunity Analysis
1. Nanomedicine: Research Trends and Challenges
1. Research Trends in Nanomedicine
2. Technology Challenges
a. Issues of Long-term Stability of Nanostructures Causing Concern
b. Technical Issues in Nano-Assembly and Molecular Manufacturing are Affecting Faster Commercialization
c. Scalability Posing a Technological Challenge to Nanomedicine Initiatives
d. Available Nanomaterials and Component Technologies Need to be Better Harnessed for Nanomedicine Applications
e. Lack of Appropriate Manufacturing Standards Constrains Nanotechnology-based Applications
3. Business and Regulatory Challenges
a. Pure-Play Nanomedicine Companies Need to Integrate Technology Know-how Across a Multitude of Disciplines to Become Formidable
b. Cost of Development Could Make Nanomedicine Applications an Expensive Proposition
c. Shorter Product Life Cycles Could Accost Nanomedicine Applications
d. Nanomedicine Applications Call for Greater Clarity in Regulations That Govern Them
e. Public Perceptions About Health Hazards of Nanotechnology Require Diligent Handling and Appropriate Communication /P>
2. Drivers and Restraints to the Growth of Nanomedicine
1. Nanomedicine Growth Drivers
a. Hope that Nanoscale Efforts Could Address Unmet Medical Needs Stimulates Research
b. Targeted Therapy and Fewer Side-Effects Bolsters the Case for Nanomedicine
c. Availability of Funds Spurs Nanomedicine Research
d. Involvement of Academia and Industry and their Synergistic Collaborations Drives Nanomedicine Research
2. Nanomedicine Growth Restraints
a. Toxicity of Certain Nanomaterials and Nanoparticles Deter Their Use
b. Environmental Concerns Might Confront Nanomedicine Applications
c. Sky-High Expectations Might Not Augur Well for Nanomedicine in the Longer Term
d. Detection of Incurable Diseases Could Put Patients in a Quandary
3. Nanomedicine and Nanotechnology Funding
1. Funding in Nanotechnology--A Global Overview
2. US Nanotech Bill Provides Nearly $4 Billion for R&D
3. Nano and MEMS Projects Get Funding from MIT's Deshpande Center
4. Partners Invest $9 Million in Nanotech Center at McGill University
5. US DoD Awards $5.5 Million Grant to Probe Potential Health Effects of Nanomaterials
3. Nanotechnology in Drug Delivery and Drug Discovery: Global Developments
1. Emerging Developments in Drug Delivery and Drug Discovery - Companies
1. Enabling Formulation and Improving Compound Activity Using NanoCrystal Technology--Ireland
2. Improving Pharmacokinetics and Addressing the Challenges of Patent Extension--Israel
3. QDots for High-Content and Initial Drug Screening--USA
4. Developing Nanofluidic Living Chip for SNP Genotyping and Transcription Analysis--USA
5. LBL-Technology Enables Micro and Nano Encapsulation--Germany
6. NanoCure's Cancer Drug Delivery System--USA
7. Silicone Micro-Needles for Better Transdermal Drug Delivery--Israel
8. NanoBio Develops Anthrax Decontamination Agent--USA
2. Emerging Developments in Drug Delivery and Drug Discovery - Universities
1. Using Multifunctional Nanorods for Drug Delivery--USA
2. Making Silica Nano Test Tubes For Medical Applications--USA
3. Produce Curved Nanoscale Structures by Templating--USA
4. Nanoparticles in Multiplexers in Bioassays--Australia
5. Lab-On-Chip Concept Eliminates Microchannels--USA
6. Devising Microfluidic Memory and Control Devices--USA
4. Nanomaterials and Nanotechnology-Based Devices: Global Developments
1. Emerging Developments in Nanotechnology-Based Devices - Companies
1. pSivida's BioSilicon: Promising Technology for Applications Galore--Australia
2. Micromachined Smart Filter for Medical Sensing Applications--USA
3. Haemodialysis Device Based on Magnetic Separation Using Nanoparticles--Israel
4. BioSante Develops Nanoparticulate-Based Ricin Vaccine for Biodefense--USA
2. Emerging Developments in Nanotechnology-Based Devices - Universities
1. Nanodevice that Can Cut DNA in a Sequence-Specific Manner--USA
2. Nanotech Repair Kit for Damaged Blood Vessels--Canada
3. Fabricating Networks To Create Fluidic Factories--USA
4. Using RNA To Do Mechanical Work at the Nano Level--USA
5. Setting Up Nanotech Decoys for Viruses--USA
6. Incorporating Living Bacteria into BioMEMS--USA
7. Designing a Smart Surface that Can Reversibly Switch Properties--USA
8. Using Nanotech To Enhance the Genetic Engineering Toolkit--China
9. Controlled DNA Biped ?eWalker?f Is No Mere Novelty--USA
10. Using Nanotubes to Create Better Orthopedic Implants--Canada
11. Using Fluorescent Nanodots to Tag Faulty Genes--USA
12. Study of Buckyballs Points to Brain Damage in Fish--USA
13. Nanofibers for Bone and Neural Scaffolds--USA
14. USA--Bacterial Culture for Advanced Nanomaterial Production?
15. Bioprocessing Route to Nanomaterials--USA
16. Biological Production of Nanomaterials--USA
17. Diatom Silica Immobilizes Active Enzyme--USA
18. Nanotubes May Make Good Brain Implants--USA
19. DNA Computers May Become NanoDoctors--Israel
5. Nanotechnology Applications in Diagnostics: Global Developments
1. Emerging Developments in Diagnostics - Companies
1. QDC-Matsushita Collaboration To Develop Qdot-enhanced Disposable Diagnostic Tests--USA
2. Verigene Platform: Accurate and Easy-to-Use Gold Nanoparticle-Based Diagnostic System--USA
3. Nanoarray-Based Virus Detection Is Easy and Economical--USA
4. Bead-Based Nanotechnology for Biomedical Research and Medical Diagnostics--USA
5. Novel Technologies for Next Generation Diagnostic Test Kits and Improved Drug Screening--Israel
6. Developing Better Colorimetric Detection with Nanoparticles--USA
2. Emerging Developments in Diagnostics - Universities
1. QDots in Cancer Detection--USA
2. Multiplexed Biological Detection using Luminescent Quantum Dots--Canada
3. Very Deep Tissue Imaging Enabled by Near-IR QDots--USA
4. Single-Molecule Nanoscale Sensor Could Help with LoCs--USA
5. Using Multi-Walled Carbon Nanotube Arrays as Ultrasensitive DNA Detectors--USA
6. Using Nanowires as Genetic Sensors--USA
7. Illuminating Nanoparticles for Medical Imaging and Gene Detection--USA
8. Creating Intracellular Nanosensors--USA
9. Saliva-Based Biomonitoring Enabled by Carbon Nanotubes--USA
10. Nanosprings Hold Promise for Future Biomedical Monitoring--USA
11. Nanoscale Stress Sensor Promises to Reduce Cardiovascular Problems--USA
12. Nanoparticle Detects Blood Glucose Levels--Israel
13. Exploring Living Cells with Nanosensors--USA
14. Finding a Better Way To Analyze DNA--USA
15. Tiny Microheaters as Protein Sensors--USA
16. Illuminating Brain Tumors with Nanoparticles--USA
6. Patents; Company Listing; Contacts
1. Patents
1. Patents Related to Nanotechnology in Drug Delivery and Drug Discovery - I
2. Patents Related to Nanotechnology in Drug Delivery and Drug Discovery - II
3. Patents Related to Nanotechnology in Drug Delivery and Drug Discovery - III
4. Patents Related to Implantable Nano-materials and Nano-devices
5. Patents Related to Nanotechnology Applications in Diagnostics
2. Contacts
1. Companies
2. Universities
7. Frost & Sullivan 2004 Science and Technology Awards
1. Product Leadership Award
1. Award Description
2. Award Recipient
2. Excellence in Technology Award
1. Award Description
2. Award Recipient
3. Technology Leadership Award
1. Award Description
2. Award Recipient
4. Excellence in Research Award
1. Award Description
2. Award Recipient
5. Enabling Technologies Award
1. Award Description
2. Award Recipient
8. Decision Support Database
1. Decision Support Database
1. Total Healthcare Expenditure
2. Pharmaceutical R&D Expenditure
3. Pharmaceutical Expenditure as a Percentage of the Market
4. Government Investment in Biotechnology
5. Private Investment in Biotechnology
6. Biotech Patents with USPTO
7. European Biotech Patents